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KMID : 1211620100050020265
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Journal of the Korean Society of Physical Medicine
2010 Volume.5 No. 2 p.265 ~ p.272
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Effects of Electroacupuncture on Activity of GOT, GPT, LDH and Functional Recovery in the Motor Injury Rats by the 6-hydroxydopamine
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Ha Mi-Sook
Rho Min-Hee
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Abstract
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Purpose: This study was investigated the effect of electroacupuncture stimulation on the change of blood biochemical components in the rat spinal cord injury(SCI) damaged by the 6-hydroxydopamine.
Methods: SCI model rats were damaged in L1-L2 injected with 6-hydroxydopamine. The thirty Sprague-Dawley adult male rats were randomly divided into normal group, control group and electroacupuncture group. Experimental groups were applied as electroacupuncture(Es-160, ITO, Japan) for 15minutes during the low frequency(2 Hz) stimulation to zusanli. The enzyme concentration levels analysis of the hematological changes were measured of Glutamate Oxaloacetate Transaminase(GOT), Glutamate Pyruvate Transaminase(GPT), Lactate dehydrogenase(LDH) and motor function recovery change was evaluated by the rota-rod test.
Results: This study were as follow : The concentration of GOT, LDH in experimental group was lower than control group(p<.05). The experimental group showed increase of motor function recovery more in compared to control group(p<.05).
Conclusion: The results of this study showed that electroacupuncture to zusanli point have an effect on functional recovery after the 6-hydroxydopamine induced SCI in rats.
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KEYWORD
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Electroacupuncture, Rota-rod test, Enzyme, Spinal cord injury
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